Maternal treatment of rats with the new pyridoindole antioxidant during pregnacy and lactation resulting in improved offspring hippocampal resistance to ischemia in vitro.

Gáspárová Z, Snirc V, Stolc S, Dubovický M, Mach M, Ujházy E.

Journal Article 2010; 31(3): 348-352 PubMed PMID: 20588238 Keywords: Action Potentials:drug effects, Animals, Antioxidants:therapeutic use, Brain Ischemia:prevention & control, Female, Hippocampus:drug effects, In Vitro Techniques, Indoles:therapeutic use, Lactation, Pregnancy, Pregnancy Complications, Cardiovascular:drug .

OBJECTIVE: Damage to the developing brain may be caused by maternal environment, nutritional deficiencies, failure of protective mechanisms, etc. Further, the developing brain may be damaged by intrauterine ischemia or by ischemia in newborns complicated by perinatal asphyxia. There is an effort to find agents with neuroprotective effec.....

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Vol. 31 (3) 2010 Neuro endocrinology letters

Maternal treatment of rats with the new pyridoindole antioxidant during pregnacy and lactation resulting in improved offspring hippocampal resistance to ischemia in vitro.

Activities of respiratory chain complexes and citrate synthase influenced by pharmacologically different antidepressants and mood stabilizers.

Cognitive disorders in type 2 diabetic patients with recognized depression.

Complication rates in the second and third trimester of spontaneous twin pregnancies and twin pregnancies after in vitro fertilization.

Distribution of ghrelin-producing cells in stomach and the effects of ghrelin administration in the house musk shrew (Suncus murinus).

Effect of mitogen lectin on lymphocyte or brain cortex cell activation.

Evaluation of the association between the CYP19 Tetranucleotide (TTTA)n polymorphism and polycystic ovarian syndrome(PCOS) in Han Chinese women.

External hydrogen peroxide is not indispensable for experimental induction of lipid peroxidation via Fenton reaction in porcine ovary homogenates.

Germ cell tumor presenting as sellar mass with suprasellar extension and long history of hypopituitarism.

Glycoxidative and nitrosative stress in kidney of experimental diabetic rats: effects of the prydoindole antioxidant stobadine.

High prevalence of obesity in patients with non-functioning adrenal incidentalomas.

Hyperreactio luteinalis in spontaneous singleton pregnancy.

Importance of screening serological examination of umbilical blood and the blood of the mother for timely diagnosis of congenital toxoplasmosis and toxocariasis.

Leptin/adiponectin ratio in obese women with and without binge eating disorder.

Melatonin restores the basal level of lipid peroxidation in rat tissues exposed to potassium bromate in vitro.

Neonatal and maternal concentrations of hydroxil radical and total antioxidant system: protective role of placenta against fetal oxidative stress.

Neuroendocrine evidence of normal hypothalamus-pituitary dopaminergic function in Huntington's disease.

Posterior Reversible Encephalopathy Syndrome (PRES) in 5-year-old girl with nephrotic syndrome.

Presence of secretory cellular apoptosis susceptibility protein in cerebrospinal fluids of patients with intracerebral hemorrhage caused by stroke and neurotrauma.

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Reducing symptoms in women with chronic anorexia nervosa. A pilot study on the effects of bright light therapy.

Spinal cord atrophy in triple A syndrome associated with a novel compound heterozygous mutation.

Suppression of melatonin secretion in healthy subjects with eyeglass LED delivery system.

The role of environmental factors in autoimmune thyroiditis.

Women with incorrect pelvic floor statics: a biomechanical answer to the mechanical loading of the vagina-endopelvic fascia complex.