Vol. 23 (2) 2002 Neuro endocrinology letters

Changes in the effect of testosterone on hypothalamic nitric oxide synthetase during sexual maturation. Its relationship with GnRH release.

OBJECTIVES: To determine the effect of testosterone administration to prepubertal (15 days old) and peripubertal rats (30 days old) on hypothalamic nitric oxide synthetase (NOS), and GnRH release.

METHODS: Hypothalamic samples containing the anterior preoptic and medial basal areas (APO-MBH) were incubated for 30.....