Vol. 21 (5) 2000 Neuro endocrinology letters

Negative immunoregulatory effects of noradrenaline through alpha2-adrenoceptor activation.

: BACKGROUND: There are some reports that catecholamines and beta-adrenoceptor agonists may suppress some immune functions. OBJECTIVES: The present study was carried out in order to examine the effects of noradrenaline (10-5 M, 10-6 M and 10-7 M), yohimbine (10-5 M, 10-6 M and 10-7 M), an alpha2-adrenoceptor antagonist, and clonidine (1.....