Opioid modulation of hypothalamic catecholaminergic neurotransmission and the pre-ovulatory LH surge in the rat.
: We have investigated the inter-relationship between the opioid and catecholaminergic systems in the control of LH secretion, and the involvement of &mgr;- and kappa-opioid subtypes in this process. Conscious female rats were intraperitoneally injected with either &mgr;- (diamorphine) or kappa-opioid agonists (U-50488H) alone or with t.....
