Vol. 20 (1-2) 1999 Neuro endocrinology letters

Activation of the inflammatory response system: A new look at the etiopathogenesis of major depression.

: Major depression is accompanied by various direct and indirect indicators of a moderate activation of the inflammatory response system (IRS). Increased production of proinflammatory cytokines, such as interleukin-1 (IL-1), IL-6 and interferon (IFNgamma), may play a crucial role in the immune and acute phase response in depression. Low.....