Articles by author - Marie Stiborova

Effect of chicken antibodies on inflammation in human lung epithelial cell lines.

Kubickova B, Majerova B, Hadrabova J, Noskova L, Stiborova M, Hodek P.

Journal Article 2014; 35(Suppl 2): 99-104 PubMed PMID: 25638373  Keywords:  Animals, Antibodies:immunology, Bacterial Infections:prevention & control, Cell Line, Chickens, Egg Yolk:immunology, Epithelial Cells:immunology, Humans, Immunoglobulin Fab Fragments:immunology, Immunoglobulins:immunology, Inflammation:immunology, Lung:im.    Citation

OBJECTIVES: As an alternative therapeutic approach for the prevention and treatment of bacterial infections with P. aeruginosa of.....

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Alcoholic liver cirrhosis increases the risk of left ventricular diastolic dysfunction.

Brotanek J, Ort M, Kubanek M, Stiborova M.

Journal Article 2013; 34(Suppl 2): 64-70 PubMed PMID: 24362094  Keywords:  Adult, Blood Flow Velocity, Case-Control Studies, Diastole, Echocardiography, Doppler, Female, Humans, Liver Cirrhosis, Alcoholic:diagnostic imaging, Male, Middle Aged, Risk Factors, Ventricular Dysfunction, Left:diagnostic imaging,.    Citation

OBJECTIVES: The aim of this study was to prove that the incidence of the more unusual and largely under-researched cardiac dysfunction, i......

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Oxidation of carcinogenic benzo[a]pyrene by human and rat cytochrome P450 1A1 and its influencing by cytochrome b5 - a comparative study.

Indra R, Moserova M, Sulc M, Frei E, Stiborova M.

Comparative Study 2013; 34(Suppl 2): 55-63 PubMed PMID: 24362093  Keywords:  Animals, Benzo(a)pyrene:metabolism, Carcinogens:metabolism, Cytochrome P-450 CYP1A1:metabolism, Cytochromes b5:pharmacology, Humans, Inactivation, Metabolic, Male, Microsomes, Liver:drug effects, Oxidation-Reduction, Rats,.    Citation

OBJECTIVES: Cytochrome P450 (CYP) 1A1 is the most important enzyme in both activation and detoxification of carcinogenic benzo[a]pyrene (B.....

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The effect of benzo[a]pyrene on metabolic activation of anticancer drug ellipticine in mice.

Stiborova M, Cerna V, Moserova M, Arlt V, Frei E.

Journal Article 2013; 34(Suppl 2): 43-54 PubMed PMID: 24362092  Keywords:  Animals, Antineoplastic Agents:pharmacokinetics, Benzo(a)pyrene:pharmacology, Biotransformation:drug effects, Cytochrome P-450 CYP1A1:metabolism, Cytochrome P-450 CYP1A2:metabolism, Cytochrome P-450 Enzyme System:metabolism, Drug Evaluation, Preclinical, .    Citation

OBJECTIVES: The aim of this study was to investigate a role of cytochrome P450 (CYP) and peroxidase in ellipticine oxidative activation in.....

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Mapping of interaction between cytochrome P450 2B4 and cytochrome b5: the first evidence of two mutual orientations.

Sulc M, Jecmen T, Snajdrova R, Novak P, Martinek V, Hodek P, Stiborova M, Hudecek J.

Journal Article 2012; 33(Suppl 3): 41-47 PubMed PMID: 23353842  Keywords:  Animals, Aryl Hydrocarbon Hydroxylases:chemistry, Carbodiimides:chemistry, Chromatography, Liquid:methods, Cross-Linking Reagents:chemistry, Cytochrome P450 Family 2, Cytochromes b5:chemistry, Dimerization, Electrons, Mass Spectrometry:methods, Microsomes.    Citation

OBJECTIVES: The cytochrome P450 (P450) and cytochrome b5 are membrane hemoproteins composing together with flavoprotein NADPH:P450 reducta.....

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Effects of cytochrome P450 inhibitors on peroxidase activity.

Martinkova M, Kubickova B, Stiborova M.

Comparative Study 2012; 33(Suppl 3): 33-40 PubMed PMID: 23353841  Keywords:  Benzoflavones:chemistry, Cytochrome P-450 Enzyme Inhibitors, Disulfiram:chemistry, Ditiocarb:chemistry, Ellipticines:chemistry, Enzyme Activation:drug effects, Enzyme Inhibitors:chemistry, Horseradish Peroxidase:antagonists & inhibitors, Humans, Ketoconaz.    Citation

OBJECTIVES: Of several enzymes metabolizing xenobiotics, cytochrome P450 (CYP) and peroxidase enzymes seem to be most important. One of th.....

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