Articles by author - Jana Hrebackova

Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma.

Poljakova J, Hrebackova J, Dvorakova M, Moserova M, Eckschlager T, Hrabeta J, Göttlicherova M, Kopejtkova B, Frei E, Kizek R, Stiborova M.

Journal Article 2011; 32(Suppl 1): 101-116 PubMed PMID: 22167207  Keywords:  Animals, Antineoplastic Combined Chemotherapy Protocols:pharmacology, Brain Neoplasms:drug therapy, DNA Damage, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Ellipticines:administration & dosage, Histone Deacetylase Inhibitors:administra.    Citation

OBJECTIVES: Valproic acid (VPA) and trichostatin A (TSA) exert antitumor activity as histone deacetylase inhibitors, whereas ellipticine a.....

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