Articles by author - Zhikun Guo

Malignant insulinoma: Report of 6 patients and literature review.

Shao Y, Qu Y, Wang X, Song Z, Guo Q, Dou J, Ba J, Lü Z, Mu Y.

Case Reports 2016; 37(3): 189-192 PubMed PMID: 27618603  Keywords:  Adult, Diazoxide:therapeutic use, Diuretics:therapeutic use, Female, Humans, Hypoglycemia:drug therapy, Insulinoma:pathology, Liver Neoplasms:pathology, Male, Middle Aged, Pancreatic Neoplasms:pathology, Retrospective Studies, Young Adult,.    Citation

OBJECTIVE: Patients with malignant insulinoma always present with symptoms of severe hypoglycemia and have poor life expectancy. In additi.....

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Sonic hedgehog overexpression regulates the neuroepithelial cells proliferation in the spinal cord of dorsal regions during chicken embryo development.

Yang C, Li X, Liu Y, Li H, Guo Z, Lin J.

Journal Article 2015; 36(4): 380-386 PubMed PMID: 26454495  Keywords:  Animals, Chick Embryo:growth & development, Chickens:growth & development, Embryonic Development:genetics, Gene Expression Regulation, Developmental:genetics, Hedgehog Proteins:metabolism, Neuroepithelial Cells:physiology, Spinal Cord:growth & development.    Citation

OBJECTIVE: Sonic hedgehog(SHH) is early expressed in the floor plate and notochord during the development of chicken embryo, which is requ.....

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The ABCD2 score may underestimate the short-term risk of stroke in Chinese population: A meta-analysis.

Chu T, Yu W, Wang Y, Guo N, He J, Shao Y, Mang J, Xu Z.

Journal Article 2015; 36(3): 262-268 PubMed PMID: 26313394  Keywords:  China:epidemiology, Humans, Ischemic Attack, Transient:epidemiology, Severity of Illness Index, Stroke:diagnosis,.    Citation

OBJECTIVES: The ABCD2 score has been commonly used to triage patients with transient ischemic attack (TIA) who are at high risk for immine.....

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Levothyroxine replacement therapy with vitamin E supplementation prevents the oxidative stress and apoptosis in hippocampus of hypothyroid rats.

Guo Y, Wan S, Zhong X, Zhong M, Pan T.

Journal Article 2014; 35(8): 684-690 PubMed PMID: 25702296  Keywords:  Animals, Apoptosis:drug effects, Dietary Supplements, Disease Models, Animal, Drug Therapy, Combination, Hippocampus:drug effects, Hormone Replacement Therapy, Hypothyroidism:drug therapy, Male, Oxidative Stress:drug effects, Random Allocation, Rats.Rats.    Citation

OBJECTIVE: To examine the effect of levothyroxine (L-T4), vitamin E or both on oxidative stress status and hippocampal apoptosis in a prop.....

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BDNF attenuates IL-1β-induced F-actin remodeling by inhibiting NF-κB signaling in hippocampal neurons.

Cai Z, Zhang X, Wang G, Wang H, Liu Z, Guo X, Yang C, Wang X, Wang H, Shu C, Xiao L.

Journal Article 2014; 35(1): 13-19 PubMed PMID: 24625911  Keywords:  Actins:chemistry, Animals, Brain-Derived Neurotrophic Factor:physiology, Female, Hippocampus:cytology, Interleukin-1beta:physiology, NF-kappa B:antagonists & inhibitors, Neurons:cytology, Rats, Rats, Wistar, Signal Transduction:physiology,.    Citation

OBJECTIVES: To examine the effect of BDNF on F-actin during the stimulation of IL-1β in hippocampal neurons.

MATERIALS & M.....

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