Vol. 37 (Suppl 1) 2016 Neuro endocrinology letters

Celecoxib is an inhibitor of enzyme acetylcholinesterase.

OBJECTIVES: Celecoxib is a nonsteroidal anti-inflammatory drug inhibiting enzyme cyclooxygenase-2 (COX-2). The drug was introduced in 1990s. In the work presented here, affinity of celecoxib to enzyme acetylcholinesterase (AChE) is inferred.

METHODS: Inhibition of human AChE by celecoxib was tested.....