The significance of 1793G>A polymorphism in MTHFR gene in women with first trimester recurrent miscarriages.

Seremak-Mrozikiewicz A, Drews K, Kurzawinska G, Bogacz A, Grzeskowiak E, Mrozikiewicz P.

Journal Article 2010; 31(5): 717-723 PubMed PMID: 21173738 Keywords: 5,10-Methylenetetrahydrofolate Reductase (FADH2):genetics, Abortion, Habitual:enzymology, Adult, Case-Control Studies, Female, Genetic Predisposition to Disease, Humans, Poland, Polymerase Chain Reaction, Polymorphism, Restriction Fragment Length, Polymor.

BACKGROUND: Recurrent miscarriages (RM) are significant social and clinical problem. One of suggested reason of RM is hyperhomocysteinemia. Polymorphic genes involved in homocysteine and folate metabolism, including 5,10-methylenetetrahydrofolate reductase (MTHFR) gene, are considered as an important risk factors for homocysteine accumu.....

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Vol. 31 (5) 2010 Neuro endocrinology letters

The significance of 1793G>A polymorphism in MTHFR gene in women with first trimester recurrent miscarriages.

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