Vol. 30 (3) 2009 Neuro endocrinology letters

Guaifenesin enhances the analgesic potency of ibuprofen, nimesulide and celecoxib in mice.

OBJECTIVES: Previously, we found that guaifenesin enhances analgesia induced by paracetamol. The aim of the present study was to determine whether guaifenesin is able to also increase analgesic activity in the non-steroid anti-inflammatory drugs ibuprofen, nimesulide and celecoxib. In addition we investigated the influence of guaifenesi.....