Vol. 23 (3) 2002 Neuro endocrinology letters

The effect of pyridoxine administration on melatonin secretion in normal men.

OBJECTIVES: To determine pineal response to pyridoxine in normal men.

MATERIAL AND METHODS: Twelve healthy men were given orally pyridoxine (100 mg) or placebo at 1700h. Serum melatonin levels were determined every 30 minutes with simultaneous measurement of core body temperature between 1700h to 0300h. Polysomno.....