Risk of single and combined exposure of birds to non-steroidal anti-inflammatory drugs and lead.

Journal Article 2012; 33(Suppl 3): 145-150 PubMed PMID: 23353858 Keywords: Animals, Anti-Inflammatory Agents, Non-Steroidal:toxicity, Blood Proteins:metabolism, Coturnix, Diclofenac:toxicity, Drug Synergism, Environmental Pollutants:toxicity, Gastrointestinal Tract:drug effects, Hemoglobins:metabolism, Lead:toxicity, Lead Poison.

OBJECTIVES: Pharmaceuticals and heavy metals such as diclofenac and lead, respectively, have been identified as environmental contaminants.....

Tacrine is implicated in oxidative stress in the laboratory guinea pig model.

Journal Article 2012; 33(Suppl 3): 136-144 PubMed PMID: 23353857 Keywords: Alzheimer Disease:chemically induced, Animals, Antioxidants:metabolism, Brain:drug effects, Caspase 3:metabolism, Chemical and Drug Induced Liver Injury:metabolism, Cholinesterase Inhibitors:toxicity, Disease Models, Animal, Female, Guinea Pigs, Heart:dru.

OBJECTIVES: Tacrine was the first acetylcholinesterase inhibitor approved for the treatment of Alzheimer disease. The compound is not avai.....

Journal Article 2012; 33(Suppl 3): 53-59 PubMed PMID: 23353844 Keywords: Animals, BALB 3T3 Cells:cytology, Chick Embryo, Chickens, Chorioallantoic Membrane:cytology, Cornea:cytology, Dose-Response Relationship, Drug, Embryo, Nonmammalian:cytology, In Vitro Techniques, Insecticides:toxicity, Irritants:toxicity, Linear Models, M.

OBJECTIVES: Malathion is generally not classified as toxic. However, the toxicity seems to be species-dependent. Local and systemic toxici.....

Journal Article 2011; 32(Suppl 1): 95-100 PubMed PMID: 22167216 Keywords: Alkaloids:pharmacology, Animals, Antioxidants:metabolism, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, FMN Reductase:metabolism, Glutathione Reductase:metabolism, Guinea Pigs, Homeostasis:drug effects, Models, Animal, Models, Biological.

OBJECTIVES: Alzheimer's disease (AD) is a neurodegenerative disorder. Symptomatic treatment is available by inhibitors of acetylcholineste.....

Comparative Study 2011; 32(Suppl 1): 77-83 PubMed PMID: 22167214 Keywords: Acetylcholinesterase:blood, Animals, Antioxidants:metabolism, Caspase 3:blood, Cholinesterase Inhibitors:toxicity, Disease Reservoirs, Environmental Exposure, Francisella tularensis:pathogenicity, Hares, Insecticides:toxicity, Male, Paraoxon:toxicity, Ran.

OBJECTIVES: The causative agent of tularemia Francisella tularensis is highly infectious and lagomorphs are important reservoirs and a sou.....

Evaluation Studies 2010; 31(Suppl 2): 62-68 PubMed PMID: 21187825 Keywords: Animals, Antidotes:pharmacology, Antioxidants:pharmacology, Glutathione Reductase:metabolism, Liver:drug effects, Male, Models, Animal, Oxidative Stress:drug effects, Oximes:pharmacology, Pyridinium Compounds:pharmacology, Radiation, Ionizing, Rats, Rats,.

OBJECTIVES: HI-6 is an antidotum suitable for treatment of intoxication by nerve agents. The recent investigation appointed its modulation.....