Martinek V, Kubickova B, Arlt V, Frei E, Schmeiser H, Hudecek J, Stiborova M.
Comparative Study 2011; 32(Suppl 1): 57-70 PubMed PMID: 22167209 Keywords: Acetyltransferases:chemistry, Animals, Aristolochic Acids:chemistry, Biotransformation:physiology, Catalytic Domain, Cells, Cultured, DNA Adducts:metabolism, Enzyme Activation, Humans, Lactams:metabolism, Models, Molecular, Molecular Conformation, NAD(P)H. CitationOBJECTIVES: Ingestion of aristolochic acid (AA) is associated with development of urothelial tumors linked with aristolochic acid nephropa.....
Martinek V, Kubickova B, Arlt V, Frei E, Schmeiser H, Hudecek J, Stiborova M. Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases. Neuro Endocrinol Lett. 2011 Jan; 32(Suppl 1): 57-70
Mizerovska J, Dracinska H, Arlt V, Schmeiser H, Frei E, Stiborova M.
Journal Article 2009; 30(Suppl 1): 52-59 PubMed PMID: 20027145 Keywords: Animals, Benz(a)Anthracenes:metabolism, Chromatography, High Pressure Liquid:methods, Cytochrome P-450 Enzyme Inhibitors, Cytochrome P-450 Enzyme System:metabolism, Humans, Inhibitory Concentration 50, Kinetics, Male, Microsomes, Liver:enzymology, Oxidati. CitationOBJECTIVES: 3-Aminobenzanthrone (3-ABA) is the main human metabolite of carcinogenic environmental pollutant 3-nitrobenzanthrone (3-NBA). .....
Mizerovska J, Dracinska H, Arlt V, Schmeiser H, Frei E, Stiborova M. Oxidation of 3-aminobenzanthrone, a human metabolite of carcinogenic environmental pollutant 3-nitrobenzanthrone, by cytochromes P450 - similarity between human and rat enzymes. Neuro Endocrinol Lett. 2009 Jan; 30(Suppl 1): 52-59
Stuerenburg H, Arlt S, Mueller-Thomsen T.
Journal Article 2006; 27(4): 535-537 PubMed PMID: 17136019 Keywords: Aged, Aged, 80 and over, Alzheimer Disease:complications, Cognition Disorders:etiology, Depression:etiology, Female, Humans, Hypothyroidism:complications, Male, Middle Aged, Thyroxine:blood,. Citation: The role of thyroid function in Alzheimer's disease (AD) has been subject to a number of studies during the last years. We investigated .....
Stuerenburg H, Arlt S, Mueller-Thomsen T. Free thyroxine, cognitive decline and depression in Alzheimer's disease. Neuro Endocrinol Lett. 2006 Aug; 27(4): 535-537
Stuerenburg H, Ganzer S, Arlt S, Müller-Thomsen T.
Journal Article 2005; 26(3): 261-263 PubMed PMID: 15990733 Keywords: Aged, Alzheimer Disease:blood, Cognition Disorders:blood, Depression:blood, Female, Folic Acid:blood, Humans, Lipoproteins:blood, Male, Risk Factors, Severity of Illness Index, Smoking:blood,. Citation: The risk for Alzheimer's disease (AD) is associated with lifestyle factors, especially cigarette smoking. In this study we investigated .....
Stuerenburg H, Ganzer S, Arlt S, Müller-Thomsen T. The influence of smoking on plasma folate and lipoproteins in Alzheimer disease, mild cognitive impairment and depression. Neuro Endocrinol Lett. 2005 Jun; 26(3): 261-263
Kolarik M, Indra R, Adam V, Heger Z, Kopeckova K, Arlt V, Stiborova M.
Journal Article 2019; 39(7): 515-524 PubMed PMID: 30860683 Keywords: Anilides:pharmacology, Animals, Cytochrome P-450 Enzyme Inhibitors:pharmacology, Ellipticines:pharmacokinetics, Humans, Microsomes, Liver:drug effects, Oxidation-Reduction:drug effects, Peroxidases:antagonists & inhibitors, Phenylurea Compounds:pharmacolo. CitationOBJECTIVES: Vandetanib¸ lenvatinib, and cabozantinib are tyrosine kinase inhibitors (TKIs) targeting VEGFR subtypes 1 and 2, EGFR and the.....
Kolarik M, Indra R, Adam V, Heger Z, Kopeckova K, Arlt V, Stiborova M. Tyrosine kinase inhibitors vandetanib, lenvatinib and cabozantinib modulate oxidation of an anticancer agent ellipticine catalyzed by cytochromes P450 in vitro. Neuro Endocrinol Lett. 2019 Feb; 39(7): 515-524