Melatonin,
Dehydroepiandrosterone and
RZR/ROR-Ligand CGP 52608
Attenuate the Stress-Induced Gastric Lesion Formation in
Rats by A. Gruszka, J. Kunert-Radek, M. Pawlikowski
and
M. Karasek
Received:
November 25, 1997
Accepted: December 3, 1997
Abstract
The
effects of melatonin, dehydroepiandrosterone and CGP 52608 (RZR/ROR-ligand),
on gastric lesions induced by the immobilization stress were
studied in rats. The administration of all studied substances
prior to immobilization caused a significant reduction in the
severity of lesions in comparison with the control group, exemplified
by a decrease in the number of lesions and their length.
